2-(2,5-dioxopyrrolidin-1-yloxy)-1,3-dimethyl-3,4,5,6-tetrahydropyrimidin-1-ium hexafluorophosphate(V) - Names and Identifiers
Name | Pyrimidinium,2-[(2,5-dioxo-1-pyrrolidinyl)oxy]-1,4,5,6-tetrahydro-1,3-dimethyl-,hexafluorophosphate(1-)
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Synonyms | Pyrimidinium,2-[(2,5-dioxo-1-pyrrolidinyl)oxy]-1,4,5,6-tetra... HPD-OSU O-Succinimidyl-1,3-dimethylpropyleneuronium hexafluorophosphate 2-(2,5-dioxopyrrolidin-1-yloxy)-1,3-dimethyl-3,4,5,6-tetrahydropyrimidin-1-ium hexafluorophosphate(V) PyriMidiniuM,2-[(2,5-dioxo-1-pyrrolidinyl)oxy]-1,4,5,6-tetrahydro-1,3-diMethyl-,hexafluorophosphate(1-) Pyrimidinium,2-[(2,5-dioxo-1-pyrrolidinyl)oxy]-1,4,5,6-tetrahydro-1,3-dimethyl-,hexafluorophosphate(1-)
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CAS | 443305-33-7
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2-(2,5-dioxopyrrolidin-1-yloxy)-1,3-dimethyl-3,4,5,6-tetrahydropyrimidin-1-ium hexafluorophosphate(V) - Physico-chemical Properties
Molecular Formula | C10H16F6N3O3P
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Molar Mass | 371.22 |
Melting Point | 170-172 °C |
Storage Condition | Room Temprature |
2-(2,5-dioxopyrrolidin-1-yloxy)-1,3-dimethyl-3,4,5,6-tetrahydropyrimidin-1-ium hexafluorophosphate(V) - Introduction
Pyrimidinium,2-[(2,5-dioxo-1-pyrrolidinyl)oxy]-1,4,5,6-tetrahydro-1,3-dimethyl-,hexafluorophosphate(1-), often abbreviated as PyBOP, is an organic compound. The following is a description of PyBOP's nature, uses, methods, and safety information:
Nature:
-Appearance: White crystalline powder
-Molecular formula: C19H19F6N5O3P
-Molecular weight: 505.3g/mol
-melting point: about 190-192°C (according to official data)
-Insoluble in water, soluble in organic solvents such as dimethyl sulfoxide (DMSO), dichloromethane, acetonitrile, etc.
Use:
PyBOP is a commonly used amino acid and peptide activation reagent, which is used for peptide bond coupling reaction in organic synthesis. It is widely used in solid phase synthesis, solution phase synthesis and synthesis of bioactive peptides. In addition, PyBOP can also be used to gestate peptide drugs and other organic synthesis fields.
Preparation Method:
PyBOP synthesis method is more complex, generally can be obtained by the substitution reaction of 2,5-dicarbonyl pyrrolidine.
Safety Information:
PyBOP is relatively safe for human health at low concentrations, but the following safety issues still need to be paid attention:
-May be irritating to skin, eyes and mucous membranes, protective measures should be taken when touching.
-When using or storing, keep away from ignition and oxidizing agents.
- PyBOP is a combustible substance and may be a fire or explosion hazard for large amounts of dust or liquid form.
-Good ventilation should be used, and care should be taken to avoid inhaling aerosols or dust.
-If taken by mistake or inhaled, seek medical assistance and show your product safety data sheet to your doctor.
Last Update:2024-04-09 02:00:46